About the book

Biomechatronic Design in Biotechnology presents a complete methodology of biomechatronics, an emerging variant of the mechatronics field that marries biology, electronics, and mechanics to create products where biological and biochemical, technical, human, management-and-goal, and information systems are combined and integrated in order to solve a mission that fulfills a human need. A biomechatronic product includes a biological, mechanical, and electronic part.

Beginning with an overview of the fundamentals and theory behind biomechatronic technology, this book describes how general engineering design science theory can be applied when designing a technical system where biological species or components are integrated. Some research methods explored include schemes and matrices for analyzing the functionality of the designed products, ranking methods for screening and scoring the best design solutions, and structuring graphical tools for a thorough investigation of the subsystems and sub-functions of products.

Contents:

1 Introduction 1

PART I FUNDAMENTALS 13

2 Conceptual Design Theory 15

3 Biotechnology and Mechatronic Design 37

4 Methodology for Utilization of Mechatronic Design Tools 49

PART II APPLICATIONS 65

5 Blood Glucose Sensors 67

6 Surface Plasmon Resonance Biosensor Devices 85

7 A Diagnostic Device for Helicobacter pylori Infection 113

8 Microarray Devices 135

9 Microbial and Cellular Bioreactors 153

10 Chromatographic Protein Purification 193

11 Stem Cell Manufacturing 215

12 Bioartificial Organ-Simulating Devices 229

13 Applications to Process Analytical Technology and Quality by Design 249